Somdet Srichairatanakool Selected Research

Deferiprone

7/2021	Identifying a Deferiprone-Resveratrol Hybrid as an Effective Lipophilic Anti-Plasmodial Agent.
12/2019	Deferiprone and efonidipine mitigated iron-overload induced neurotoxicity in wild-type and thalassemic mice.
3/2017	Effects of iron overload, an iron chelator and a T-Type calcium channel blocker on cardiac mitochondrial biogenesis and mitochondrial dynamics in thalassemic mice.
1/2016	Combined Iron Chelator and Antioxidant Exerted Greater Efficacy on Cardioprotection Than Monotherapy in Iron-Overloaded Rats.
9/2015	Inhibitory effect of novel iron chelator, 1-(N-acetyl-6-aminohexyl)-3-hydroxy-2-methylpyridin-4-one (CM1) and green tea extract on growth of Plasmodium falciparum.
5/2015	Characterisation of a novel oral iron chelator: 1-(N-Acetyl-6-Aminohexyl)-3-Hydroxy-2-Methylpyridin-4-one.
1/2015	Effects of Iron Chelators on Pulmonary Iron Overload and Oxidative Stress in β-Thalassemic Mice.
9/2014	Iron distribution and histopathological characterization of the liver and heart of β-thalassemic mice with parenteral iron overload: Effects of deferoxamine and deferiprone.
4/2013	Deferiprone (GPO-L-ONE(®) ) monotherapy reduces iron overload in transfusion-dependent thalassemias: 1-year results from a multicenter prospective, single arm, open label, dose escalating phase III pediatric study (GPO-L-ONE; A001) from Thailand.
1/2006	Iron-chelating and free-radical scavenging activities of microwave-processed green tea in iron overload.

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Somdet Srichairatanakool Research Topics

Disease

27	Iron Overload 07/2021 - 01/2006
19	Thalassemia 01/2021 - 08/2009
6	Anemia 09/2021 - 01/2015
6	Malaria 09/2021 - 04/2012
5	Cardiomyopathies (Cardiomyopathy) 01/2018 - 02/2011
4	Neoplasms (Cancer) 06/2022 - 04/2014
4	Left Ventricular Dysfunction 01/2021 - 01/2015
4	beta-Thalassemia (Cooley's Anemia) 01/2021 - 01/2006
3	Inflammation (Inflammations) 06/2022 - 12/2019
3	Hemolysis 09/2021 - 01/2016
3	Mitochondrial Diseases (Mitochondrial Disease) 12/2019 - 01/2016
3	Fibrosis (Cirrhosis) 09/2016 - 01/2015
2	Flatulence 06/2022 - 01/2019
2	Infections 09/2021 - 12/2013
2	Neuroblastoma 01/2021 - 05/2020
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021 - 04/2014
2	Hepatocellular Carcinoma (Hepatoma) 10/2020 - 05/2020
2	Body Weight (Weight, Body) 01/2015 - 01/2011
2	Parasitemia 12/2013 - 04/2012
1	Pain (Aches) 10/2022
1	Constipation 06/2022
1	Insect Bites and Stings (Insect Bite) 06/2022
1	Liver Neoplasms (Liver Cancer) 03/2022
1	Frailty 03/2022
1	Iron-Deficiency Anemia (Anemia, Iron Deficiency) 10/2021
1	Breast Neoplasms (Breast Cancer) 07/2021
1	Alzheimer Disease (Alzheimer's Disease) 01/2021
1	Hypoxia (Hypoxemia) 01/2021
1	Edema (Dropsy) 01/2021
1	Parkinson Disease (Parkinson's Disease) 01/2021
1	Stomach Ulcer (Gastric Ulcer) 01/2021
1	Ulcer 01/2021
1	Necrosis 01/2020
1	Insulinoma 05/2019
1	Pulmonary Hypertension 12/2015
1	Wounds and Injuries (Trauma) 01/2015

Drug/Important Bio-Agent (IBA)

33	IronIBA 03/2022 - 01/2006
15	Chelating AgentsIBA 07/2021 - 08/2014
10	DeferiproneIBA 07/2021 - 01/2006
8	AntioxidantsIBA 10/2020 - 03/2010
7	Isoflurophate (DFP)FDA Link 09/2021 - 05/2015
7	TeaIBA 01/2021 - 01/2006
7	Deferoxamine (Desferal)FDA LinkGeneric 10/2020 - 01/2006
5	Transferrin (beta 2 Transferrin)IBA 01/2020 - 12/2015
4	Ferritins (Ferritin)IBA 01/2021 - 12/2015
4	Hemoglobins (Hemoglobin)IBA 01/2021 - 01/2015
4	Free RadicalsIBA 05/2020 - 01/2006
3	HepcidinsIBA 01/2021 - 07/2009
3	1- (N- acetyl- 6- aminohexyl)- 3- hydroxy- 2- methylpyridin- 4- oneIBA 01/2021 - 09/2014
3	T-Type Calcium Channels (T-Type Calcium Channel)IBA 12/2019 - 03/2017
3	Dextrans (Dextran)FDA Link 09/2016 - 09/2014
3	GlobinsIBA 09/2016 - 09/2014
3	Deferasirox FDA Link 01/2016 - 05/2015
2	Interleukin-6 (Interleukin 6)IBA 06/2022 - 01/2020
2	PhytochemicalsIBA 03/2022 - 04/2014
2	Antimalarials (Antimalarial Agents)IBA 09/2021 - 07/2021
2	Pharmaceutical PreparationsIBA 07/2021 - 04/2013
2	NitrogenIBA 01/2020 - 12/2013
2	Urea (Carbamide)FDA LinkGeneric 01/2020 - 12/2013
2	Proteins (Proteins, Gene)FDA Link 01/2020 - 03/2017
2	efonidipineIBA 12/2019 - 03/2017
2	epigallocatechin gallate (epigallocatechin-3-gallate)IBA 05/2019 - 12/2018
2	Hemoglobin EIBA 01/2018 - 01/2015
2	Indicators and Reagents (Reagents)IBA 12/2015 - 01/2015
1	Biomarkers (Surrogate Marker)IBA 10/2022
1	Anesthetics (Anesthetic Agents)IBA 10/2022
1	Amylases FDA Link 10/2022
1	Dinoprostone (PGE2)FDA Link 06/2022
1	Tannic Acid FDA Link 03/2022
1	Coffee FDA Link 07/2021
1	Pyrimethamine (Daraprim)FDA Link 07/2021
1	Folic Acid (Vitamin M)FDA LinkGeneric 07/2021
1	Indomethacin (Indometacin)FDA LinkGeneric 01/2021
1	Ethanol (Ethyl Alcohol)IBA 01/2021
1	Analgesics (Analgesic Drugs)IBA 01/2021
1	CarrageenanIBA 01/2021
1	Hormones (Hormone)IBA 01/2021
1	Acetic Acid (Vinegar)FDA LinkGeneric 01/2021
1	schizokinenIBA 10/2020
1	Fatty Acids (Saturated Fatty Acids)IBA 05/2020
1	LipidsIBA 05/2020
1	CurcuminIBA 01/2020
1	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2020
1	HexanesIBA 10/2019
1	2,2'-azobis(2-amidinopropane) (ABAP)IBA 08/2019
1	Bovine Serum AlbuminIBA 05/2019
1	ferric ammonium citrate FDA Link 05/2019
1	Insulin (Novolin)FDA Link 05/2019
1	ferroceneIBA 12/2018
1	Messenger RNA (mRNA)IBA 08/2017
1	Cysteine (L-Cysteine)FDA Link 01/2016
1	Malondialdehyde (Propanedial)IBA 01/2016
1	MicronutrientsIBA 09/2015
1	CatalaseIBA 01/2015

Therapy/Procedure

5	Blood Transfusion (Blood Transfusions) 01/2021 - 01/2006
2	Thai Traditional Medicine 06/2022 - 01/2019
2	Therapeutics 03/2018 - 12/2013
1	Chelation Therapy (Therapy, Chelation) 01/2020
1	Splenectomy 12/2015
1	Intraperitoneal Injections 01/2015